The British Crown responds to the colonists' destruction of 600,000 pounds of tea by sending ruthless General Gage to Boston to snuff out the rebellion. The general's tumultuous relationship with his wife, Margaret, leaves her vulnerable to sympathising with the colonists and engages in an affair with one of them. To combat the growing threat of the British, Sam Adams, John Hancock, and John Adams meet with representatives at the First Continental Congress in Philadelphia.
With Rawls looking to make a premature murder arrest in three murders linked to D'Angelo and Barksdale, McNulty and Greggs turn to an unlikely ally to secure a delay in the case and preserve the significant wiretap gains being made: Daniels.
The Detail has a setback, and needs a new co-operator, while Russell and Bunk revisit Philly, looking for evidence. Brother Mouzone talks with Stringer Bell regarding their agreement, leaving Bell to contend with a dissatisfied Avon Barksdale.
During the 1946-49 Greek Civil War, young brothers Anestis and Vlassis are recruited by opposing sides. Anestis joins the National Army while Vlassis becomes a soldier in the Democratic Army. Fighting in the countryside they grew up in, the boys become increasingly fanatical as the war progresses.